February 1, 2005European Heart Journal127 citationsOpen Access
View Full PaperImpact of gender on risk stratification by exercise and dobutamine stress echocardiography: long-term mortality in 4234 women and 6898 men
Structured PICO
Does risk stratification by exercise and dobutamine stress echocardiography predict long-term mortality similarly in women and men?
P
Population
11,132 patients (4,234 women and 6,898 men) undergoing exercise or dobutamine stress echocardiography at three hospitals.
I
Intervention
Exercise or dobutamine stress echocardiography
O
Outcome
Time to cardiac death (5-year mortality)hard clinical
Echocardiographic measures of inducible wall motion abnormalities and left ventricular function are highly predictive of long-term cardiac mortality for both women and men.
Abstract
AIMS: Prior research is limited with regard to the diagnostic and prognostic accuracy of commonplace cardiac imaging modalities in women. The aim of this study was to examine 5-year mortality in 4234 women and 6898 men undergoing exercise or dobutamine stress echocardiography at three hospitals. METHODS AND RESULTS: Univariable and multivariable Cox proportional hazards models were used to estimate time to cardiac death in this multi-centre, observational registry. Of the 11 132 patients, women had a greater frequency of cardiac risk factors (P/=16% for men with ischaemia on dobutamine stress echocardiography (P<0.0001). CONCLUSION: Echocardiographic measures of inducible wall motion abnormalities and global and regional left ventricular function are highly predictive of long-term outcome for women and men alike.