Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern.

Key Points

• The aim is to identify inhibitors of viral helicases that can act as antiviral agents against pandemic viruses.
• Developed high-throughput assays for screening antiviral compounds against viral helicases.
• Tested various compounds to determine their effectiveness as potential inhibitors.
• Identified several lead scaffolds with significant potential as antiviral agents.
• Developed assays that can be used for future screening of antiviral treatments.