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December 1, 1993Journal of Biological ChemistryOpen Access

Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.

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Authors

ITIvan TarleHoward Hughes Medical InstituteDBDavid W. BorhaniGinkgo Bioworks, Inc. (United States)DWDavid K. WilsonArkansas Children's Hospital

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Tarle et al. (1993) studied this question.

synapsesocial.com/papers/69f836f6976531054ef7688dhttps://doi.org/10.1016/s0021-9258(19)74444-5
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