Spectrum of Renal Lesions in Autopsy Cases: A Histopathological Study at a Tertiary Care Centre

Aims: To investigate the prevalence and histopathological spectrum of renal lesions in autopsy cases at a tertiary care center to identify subclinical and unsuspected renal diseases.Methods: A retrospective descriptive study of 420 autopsy cases was conducted between January and December 2023. Renal tissues were fixed in 10% neutral buffered formalin, embedded in paraffin, and stained with hematoxylin and eosin (H&E) for microscopic evaluation.Results: Definitive renal pathology was identified in 140 cases (33.33%). Tubulointerstitial lesions were the most frequent findings (45%), with acute kidney injury (AKI) accounting for 38.57% of pathological cases. Other incidental findings included simple cysts (7.85%), glomerulosclerosis (5%), renal infarction (1.42%), and metastatic carcinoma (0.71%).Conclusions: Autopsy remains a critical tool for identifying silent renal pathologies, such as subclinical AKI and incidental malignancies, which contribute to improved clinicopathological correlation and quality assurance.