Case reports reveal placental issues and neurological malformations in congenital LCMV infection, suggesting the need for screening.
Congenital lymphocytic choriomeningitis virus (LCMV) infection is associated with major neurologic malformations and fetal demise. We report 2 cases of probable congenital LCMV infection and chorioretinitis, cerebral ventriculomegaly, and placental histopathology in Philadelphia, Pennsylvania, USA. Clinicians who suspect congenital LCMV infection should screen for chorioretinitis, LCMV antibodies, and evidence of placental pathology.
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Abraham et al. (2026) studied this question.
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