Why the study?
Does D-dimer measurement accurately diagnose acute aortic syndrome in patients presenting with acute chest pain?
Does D-dimer measurement accurately diagnose acute aortic syndrome in patients presenting with acute chest pain?
D-dimer testing demonstrates high sensitivity for distinguishing acute aortic syndrome from other causes of acute chest pain, though false negatives can occur in subtypes like intramural hematoma.
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D-dimer may support ruling out acute aortic syndrome in chest pain; leaves open prospective validation before practice change.
Kotani et al. (2016) studied this question.
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