Demonstrates thermospermine's role in xylem cell fate through ribosome regulation in plants, suggesting a key developmental pathway.
The formation of xylem vessels depends on a balance between transcription factors SACLs and LHW, whose translation is controlled by thermospermine. A recent study shows that a conserved rRNA methylation by OVERACHIEVER enables thermospermine binding, allowing ribosomes to oppositely regulate SACL and LHW translation to direct plant xylem cell fate.
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Wu et al. (2026) studied this question.
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