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May 2, 2026

Synthesis, radiolabelling and preliminary evaluation of [⁶⁸Ga]Ga-DOTA-linked cyanuric chloride-glu-ureido scaffold for PSMA PET imaging.

Mohd. Faheem Vaibhav Pandey Anjali Pal Pradeep Kumar Sharma Manisha Prasad Manish Dixit

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Key Points

This research aims to develop and assess a new radiotracer for prostate cancer imaging using PET techniques.
Synthesis of [68Ga]Ga-DOTA-linked cyanuric chloride-glu-ureido scaffold
Radiolabelling process evaluation
Preliminary imaging evaluations for PSMA targeting.
The synthesized radiotracer showed high specificity for PSMA.
Efficient synthesis method yields satisfactory radiolabelling results.
Initial imaging evaluations indicate promising results for prostate cancer detection.

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Implication

Evaluates a new PSMA PET imaging tracer for prostate cancer, suggesting promising imaging capabilities.

Abstract

Ga]Ga-PSMA-C1D as a promising, efficiently synthesizable, and highly PSMA-specific PET radiotracer for imaging prostate cancer.

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Cite This Study

Faheem et al. (2026) studied this question.

synapsesocial.com/papers/69f9892215588823dae18126 https://doi.org/10.1007/s11030-026-11540-3

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