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May 5, 2026

Optimizing Indications and Diagnostic Performance of Computed Tomography Angiography in Acute Gastrointestinal Bleeding: A Large Cohort Study.

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Authors

HHHye Kyung HyunNSNak‐Hoon SonDJDong‐Hyuk Jung

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Overview

Cohort study assesses CTA's diagnostic performance and predictors in acute GI bleeding, suggesting improved indications.

Key Points

  • To assess the diagnostic performance of computed tomography angiography (CTA) and identify predictors for its optimal use in acute gastrointestinal bleeding.
  • Large cohort study conducted in Korea on patients with suspected acute GI bleeding
  • Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of CTA were assessed
  • Multivariate analysis identified predictors of positive CTA findings and a predictive nomogram was developed and validated.
  • CTA showed low sensitivity (44.9%) and PPV (52.4%), but high specificity (88.3%) and NPV (84.9%)
  • Predictive factors included male sex, antithrombotic use, low hemoglobin, high blood urea nitrogen, hemodynamic instability, and specific symptoms
  • Selective application of CTA improved sensitivity (47.3% at probability ≥0.1, 56.5% at ≥0.2, 69.5% at ≥0.3; all P < 0.001).

Cite This Study

Hyun et al. (2026) studied this question.

synapsesocial.com/papers/69f9894115588823dae18296https://doi.org/10.1016/j.gie.2026.04.023
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Role of CT-Angiography in the Acute Gastrointestinal Bleeding2024
  2. 2Visible Bleeding is the Strongest Predictor of a Positive CT Mesenteric Angiogram in the Setting of Lower Gastrointestinal Bleeding2026
  3. 3Computed Tomographic Angiography and Yield for Gastrointestinal Bleeding in the Emergency Department2025 · 4 citations
  4. 4Prognostic Value of CT Angiography Findings in Patient with Suspected Active Bleeding2025
  5. 5Comparative Analysis of the Risk of Rebleeding between Catheter Angiography and Colonoscopy Following a Positive Computed Tomography Angiography Results in Patients with Severe Lower Gastrointestinal Bleeding.2025