Why the study?
Does a multiple biomarker approach (ACE, sIL-2R, BNP, cTnI) improve the detection of cardiac involvement and prediction of fatal arrhythmia in patients with sarcoidosis?
Population
172 consecutive patients with diagnosed sarcoidosis, including non-cardiac sarcoidosis and cardiac…
Comparison
Measurement of plasma levels of… vs Comparison between non-cardiac sarcoidosis and…
Design
Cohort
Authors
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May support biomarker-guided detection and risk stratification in sarcoidosis; leaves open prospective validation before practice change.
Does a multiple biomarker approach (ACE, sIL-2R, BNP, cTnI) improve the detection of cardiac involvement and prediction of fatal arrhythmia in patients with sarcoidosis?
A multiple biomarker approach utilizing BNP for detection and cTnI for risk stratification of fatal arrhythmia can support the comprehensive management of cardiac sarcoidosis.
Kiko et al. (2018) studied this question.
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