Why the study?
Does the introduction of CTPA affect the incidence, mortality, and treatment complications of pulmonary embolism in United States adults?
Population
United States adults from the Nationwide Inpatient Sample and Multiple Cause-of-Death databases
Comparison
Time period after introduction of Computed… vs Time period before CTPA was introduced (1993–1998)
Design
Cohort
Authors
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CTPA introduction may drive PE overdiagnosis; leaves open net clinical benefit and warrants prospective trials.
Does the introduction of CTPA affect the incidence, mortality, and treatment complications of pulmonary embolism in United States adults?
The introduction of CTPA was associated with a substantial increase in pulmonary embolism incidence but a smaller reduction in mortality compared to the pre-CTPA era, suggesting potential overdiagnosis.
Wiener et al. (2010) studied this question.
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