Why the study?
Inflammation contributes to atherosclerosis and peripheral arterial disease, motivating an evaluation of the preoperative role of NLR and PLR in medium-term outcomes following surgical revascularization for femoropopliteal disease.
Do elevated preoperative NLR and PLR predict 12-month primary patency failure, amputation, and mortality in patients undergoing surgical revascularization for femoropopliteal disease?
Population
Patients with femoropopliteal disease indicated for surgical revascularization
Comparison
High vs low preoperative NLR and PLR, or patency vs nonpatency
Design
Retrospective study
Follow-up
12 months
Authors
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Elevated NLR/PLR may aid risk stratification after femoropopliteal revascularization; leaves open causal role and therapeutic targeting.
Do elevated preoperative NLR and PLR predict 12-month primary patency failure, amputation, and mortality in patients undergoing surgical revascularization for femoropopliteal disease?
Elevated preoperative NLR and PLR are strong independent predictors of 12-month primary patency failure, amputation, and mortality in patients undergoing surgical revascularization for femoropopliteal disease.
Russu et al. (2022) studied this question.
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