Dermatological Effects of Royal Jelly: From Health to Cosmetics

The skin, the body's largest and most complex organ, is the body's first line of defense against germs and harmful substances. In recent years, skin diseases that can affect people of all ages and backgrounds have become a common health problem worldwide. Researchers have been very interested in natural products over the past ten years because they have health benefits and few side effects. Honey bee products have been used since ancient times to prevent and/or treat several diseases. Royal jelly, a significant superfood, is produced by the hypopharyngeal and mandibular glands of young worker honey bees. RJ contains many bioactive molecules (10-HDA, MRJPs, royalicin, royalactin, etc.) and unique essential components, including carbohydrates, lipids, and proteins. Many studies show that RJ and its biologically active components exhibit pharmacological effects, including antioxidant, antimicrobial, anticancer, anti-inflammatory, anti-aging, neuroprotective, and antiallergic properties. This study emphasizes the dermatological effects of RJ, clarifies its biological properties, and highlights its potential advantages in formulating new topical products for cosmetic and dermatological applications.