Characterization reveals cannabinoid cross-reactivity in canine urine, suggesting implications for immunoassays.
-THC-COOH yet exhibit EIA-reactivity. Ion fragmentation patterns, derivatization behavior, and comparison to established mass spectral libraries support the possibility of 11-hydroxylated and 9-carboxylated THCV analogs. The findings point to THCV metabolism as a plausible source of EIA-cross-reactivity in canines, raising important implications for veterinary toxicology and drug screening protocols. This study contributes crucial insights into canine cannabinoid metabolism and highlights limitations of existing immunoassays when influenced by structurally-similar analytes.
No takes yet. Share an insight, caveat, or question.
Pickard et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: