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Network meta-analysis shows dexmedetomidine prevents postoperative delirium in older adults, suggesting corticosteroids may reduce severity.
The selective alpha‐2 adrenergic agonist dexmedetomidine showed the most broadly effective results in preventing postoperative delirium in older adults in a systematic review and meta‐analysis comprising 18 randomized trials. Corticosteroids were the only treatments found to reduce delirium severity.
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A 2026 study studied this question.
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