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May 6, 2026Journal of onco-anaesthesiology and perioperative medicine.Open Access

Hyperthermic Intrathoracic Chemotherapy Following Cytoreductive Surgery: A Single Centre Retrospective Analysis

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Authors

MYMonika YadavJDJyotirmoy DasSKSangeeta Khanna

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Overview

Retrospective analysis found significant increases in central venous pressure and serum lactate during CRS and hyperthermic intrathoracic chemotherapy, indicating careful perioperative management is重要

Key Points

  • To assess intraoperative changes in central venous pressure and variations in temperature and serum levels during CRS and hyperthermic intrathoracic chemotherapy.
  • Retrospective review of 10 thymoma patients undergoing CRS with cisplatin-based HITHOC
  • Analyzed demographics, preoperative diagnosis, hemodynamic data, CVP, and temperature trends
  • Monitored postoperative organ function
  • Central venous pressure and serum lactate significantly increased during hyperthermic intrathoracic chemotherapy (P = 0.002; P = 0.018)
  • No significant changes in serum creatinine or nasopharyngeal temperature were observed
  • The procedure was deemed feasible and safe with careful perioperative planning.

Cite This Study

Yadav et al. (2026) studied this question.

synapsesocial.com/papers/69fa979b04f884e66b531727https://doi.org/10.4103/joapm.joapm_85_25
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