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May 6, 2026Open Access

Phytochemical Investigation and Pharmacologicalevaluation of Annona Squamosa L. Stem Bark Extracts for Memory Enhancing Activity

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Authors

SDSoni DangatDSDr. S. K. Sarje*AIA. V. Ingle

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Overview

Experimental evaluation shows Annona squamosa extracts improve memory in rats, suggesting bioactive potential for brain health.

Key Points

  • To investigate the memory enhancing activity and phytochemical properties of Annona squamosa stem bark extracts.
  • Physical parameters assessed include ash value and solubility.
  • Extracts were obtained using Soxhlet extraction with various solvents.
  • Phytochemical standardization applied using TLC and chemical tests.
  • Memory activity evaluated through radial maze arm and Morris water maze tests in rats.
  • Acute toxicity studies performed to determine safe dosages.
  • Ethyl acetate and methanolic extracts show significant memory enhancing activity.
  • Methanolic extract demonstrated superior effects compared to ethyl acetate extract.
  • Presence of flavonoids and phenolic content likely contributes to observed activities.

Cite This Study

Dangat et al. (2025) studied this question.

synapsesocial.com/papers/69fa979b04f884e66b531876https://doi.org/10.5281/zenodo.20027050
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