Engineering reveals the potential of coumarin-based probes to assess therapy in ulcerative colitis and Parkinson's disease.
primes the probe, whereas subsequent irradiation induces coumarin-mediated singlet oxygen generation that reacts with the methylenecyclobutane unit to initiate afterglow emission. By virtue of the elimination of autofluorescence and high activation contrast, C545-MP NPs enable precise assessing therapeutic efficacy of ulcerative colitis and Parkinson's disease.
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Wang et al. (2026) studied this question.
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