An Extrinsic Enzyme-Activatable Fluorescent Probe for High-Contrast Tumor Imaging

Yifang Guo; Yuwei Du; Liru Heng; Huimin Miao; Chen Chen; Qiang Zhang; Jiayi Wang; Yige Shan; Zhang Chen; Li Li

doi:10.1039/d6sc00484a

January 1, 2026Chemical ScienceOpen Access

An Extrinsic Enzyme-Activatable Fluorescent Probe for High-Contrast Tumor Imaging

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Key Points

The aim is to develop an enzyme-activatable fluorescent probe for improved tumor imaging.
Development of a novel fluorescent probe
Evaluation of probe sensitivity in tumor tissues
Comparison of probe effectiveness in imaging malignant tumors
The fluorescent probe significantly improved imaging contrast of tumors
Enhanced detection sensitivity compared to traditional methods
Demonstrated potential for accurate diagnosis and monitoring of tumor progression

Implication

Fluorescent probe enhances tumor imaging in malignancies, suggesting improved diagnosis and treatment outcomes.

Abstract

Malignant tumors pose a major threat to human health, and the effectiveness of treatment largely depends on accurate early diagnosis and complete resection. Although fluorescence imaging offers high sensitivity and...

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Cite This Study

Guo et al. (2026) studied this question.

synapsesocial.com/papers/69fa98bd04f884e66b5326aa https://doi.org/10.1039/d6sc00484a

View Full Paper

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An Extrinsic Enzyme-Activatable Fluorescent Probe for High-Contrast Tumor Imaging

Key Points

Implication

Abstract

Discussion

Cite This Study

An Extrinsic Enzyme-Activatable Fluorescent Probe for High-Contrast Tumor Imaging

Key Points

Implication

Abstract

Discussion

Cite This Study

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