Key result
High private well use linked to ~11% lower hypertensive heart disease mortality, independent of groundwater nitrate.
Why the study?
Does groundwater nitrate concentration modify the protective association between private well use and cardiovascular mortality in Alabama?
Population
3,924 census block groups (CBGs) in Alabama, analyzing age groups 45-54, 55-64, 65-74, and 75+ from 2016-2019.
Comparison
High percent private well use and high median… vs Lower percent private well use and average/lower…
Design
Cross-sectional
Follow-up
2016 - 2019
Authors
Loading...
Groundwater nitrate concentrations do not appear to drive the observed protective association between private well use and cardiovascular mortality in Alabama, possibly due to the low overall nitrate levels in the region.
Observational (n=3,924)
Does groundwater nitrate concentration modify the protective association between private well use and cardiovascular mortality in Alabama?
Relative Risk: 0.89 (95% CI 0.83–0.95)
Groundwater nitrate concentrations do not appear to drive the observed protective association between private well use and cardiovascular mortality in Alabama, possibly due to the low overall nitrate levels in the region.
Moylan et al. (2026) conducted an observational in Hypertensive heart disease, ischemic heart disease, and stroke/cerebrovascular deaths (n=3,924). High percent private well use and median groundwater nitrate concentration vs. Lower percent private well use and lower nitrate concentration was evaluated on Hypertensive heart disease mortality (RR 0.89, 95% CI 0.83-0.95). The protective association between high private well use and hypertensive heart disease mortality (RR 0.89; 95% CI 0.83-0.95) did not significantly depend on median groundwater nitrate concentration.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: