Review highlights lef1's role in b cell maintenance and its potential for targeted therapies in cancer and autoimmunity.
In this article of the Highlights of 2025 series, we review the latest discovery of LEF1 function in B cell biology. These discoveries provide novel insights into the LEF1 function on B cell maintenance in cancer and autoimmunity, uncovering new opportunities for the development of a more specific B cell targeting approach.
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Naylor et al. (2026) studied this question.
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