Hyaluronic Acid-Based Nanofibrous Scaffolds Incorporating Nigella sativa Methanolic Extract with Multifunctional Antimicrobial, Antioxidant, An-ti-inflammatory, and Anticancer Properties for Advanced Wound Healing

Hadil Faris; Fadhil Faez Sead; Farag M. A. Altalbawy; Nawfal Y. Jamil; Ahmed Salih Sahib; Umida Tashkenbaeva; Zahraa Saad Abdulali; Mariem Alwan; Mahmood Jawad; Hiba Mushtaq; Aseel Smerat; Samar El-Tayeb Izzat

doi:10.1039/d6nj00537c

January 1, 2026New Journal of Chemistry

Hyaluronic Acid-Based Nanofibrous Scaffolds Incorporating Nigella sativa Methanolic Extract with Multifunctional Antimicrobial, Antioxidant, An-ti-inflammatory, and Anticancer Properties for Advanced Wound Healing

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Key Points

The aim is to fabricate and characterize nanofibers incorporating nigella sativa extract for skin therapeutic applications.
Electrospinning of hyaluronic acid nanofibers with nigella sativa methanolic extract.
Characterization of the nanofibers regarding structural and functional properties.
Antimicrobial activity was confirmed against various pathogens.
Demonstrated antioxidant and anti-inflammatory effects in vitro.
Significantly enhanced wound healing properties observed in preliminary tests.

Implication

Study shows hyaluronic acid nanofibers with nigella sativa extract improve wound healing, suggesting multifunctional therapeutic properties.

Abstract

The present study reports the fabrication and characterization of hyaluronic acid nanofibers in-corporated with Nigella sativa methanolic extract (HA/NSME-nanofibers) for potential skin therapeutic applications. The HA/NSME-nanofibers were successfully electrospun and...

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Cite This Study

Faris et al. (2026) studied this question.

synapsesocial.com/papers/69faa30204f884e66b533887 https://doi.org/10.1039/d6nj00537c

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Hyaluronic Acid-Based Nanofibrous Scaffolds Incorporating Nigella sativa Methanolic Extract with Multifunctional Antimicrobial, Antioxidant, An-ti-inflammatory, and Anticancer Properties for Advanced Wound Healing

Key Points

Implication

Abstract

Discussion

Cite This Study

Hyaluronic Acid-Based Nanofibrous Scaffolds Incorporating Nigella sativa Methanolic Extract with Multifunctional Antimicrobial, Antioxidant, An-ti-inflammatory, and Anticancer Properties for Advanced Wound Healing

Key Points

Implication

Abstract

Discussion

Cite This Study

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