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Biomedical utility of zinc and copper mediated cerium oxide nanoparticles | Synapse

May 6, 2026RSC Advances0 citationsOpen Access

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Biomedical utility of zinc and copper mediated cerium oxide nanoparticles

SSSamantha StoltzUniversity of Central Florida CNCraig J. NealUniversity of Central Florida EKElayaraja KolanthaiUniversity of Central Florida

Puntos clave

This research investigates the effects of zinc and copper modified cerium oxide nanoparticles on cell survival and cytotoxicity in different cell models.
In vitro testing in HUVEC for cell survival.
Testing in MCF-7 breast cancer model to assess cytotoxic effects.
Evaluation of redox-mediated surface reactions.
Zinc and copper modified nanoparticles significantly promote cell survival in HUVEC.
In MCF-7 cells, a considerable pro-oxidant, cytotoxic effect was observed.

Resumen

(Copper, Zinc) Metal (oxide)-modified cerium oxide nanoparticles promote cell survival via redox-mediated surface reactions in vitro (HUVEC); while producing a substantial pro-oxidant, cytotoxic effect in a (MCF-7 breast cancer) cancer model.

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Cite This Study

Stoltz et al. (Thu,) studied this question.

synapsesocial.com/papers/69fada7f03f892aec9b1e3f6 https://doi.org/https://doi.org/10.1039/d6ra02316a