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Reveals how N-terminal truncation and cholesterol impact p3 membrane interactions, indicating potential implications for amyloid behavior.
, which exhibits stable, multiresidue adsorption, p3 shows only transient adsorption governed by competing local electrostatic forces. These findings provide molecular insights into the reduced membrane activity of p3 and highlight essential roles of N-terminal anchoring and membrane dynamics in amyloid-membrane interactions.
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Zhou et al. (2026) studied this question.
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