Why the study?
Does sex influence the incidence and outcome of perioperative renal ischemia?
Population
Patients undergoing perioperative care and experimental models of renal ischemia/reperfusion injury
Comparison
Female sex and sex steroids vs Male sex
Design
Review
Authors
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Does not support sex-based changes in perioperative renal care; hypothesis-generating for sex steroid effects on renal ischemia.
Does sex influence the incidence and outcome of perioperative renal ischemia?
There is significant sexual dimorphism in perioperative renal ischemia, with women generally experiencing lower rates of acute renal failure except in cardiac surgery, highlighting the potential role of sex steroids in renal injury.
Hutchens et al. (2008) studied this question.
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