Case reports of cholecystitis and liver abscess due to oral bacteria imply the need for better oral hygiene and collaboration.
The concept that oral foci of infection can have systemic effects is known as “oral focal infection.” Here, we report two rare cases of hepatobiliary infections caused by oral bacteria: Porphyromonas gingivalis and Actinomyces naeslundii. Case 1 involved acute cholecystitis, whereas Case 2 presented with a liver abscess. Both patients had poor oral hygiene, suggesting hematogenous spread from the oral cavity. These cases underscore the potential for oral pathogens to cause systemic infections and highlight the importance of oral hygiene and interprofessional collaboration between medicine and dentistry for prevention.
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Kikuchi et al. (2026) studied this question.
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