The research focuses on developing a novel hydrogel to enhance bone regeneration in the mandible.
Utilized a bioactive microflower-doped triple-network hydrogel for the experiment.
Evaluated the hydrogel's capacity to modulate inflammation and promote bone healing in tests.
Analyzed the effects on angiogenesis and osteogenesis in relation to mandibular defects.
The hydrogel showed significant immunomodulation effects.
Promoted increased angiogenesis and osteogenesis in the mandibular bone.
Demonstrated potential for effective restoration of mandibular bone defects.
Abstract
This study introduces a Ca/SrP microflower-doped triple-network hydrogel that modulates inflammation, promotes angiogenesis and osteogenesis, and restores mandibular bone defects.