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May 7, 2026AntioxidantsOpen Access

High-Fiber Diet Supplemented with N-Carbamylglutamate Modulates Uterine Microbiota, Metabolites, and Transcriptome to Improve Reproductive Efficiency in Sows

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Authors

YLYaxu LiangHWHongyang WangZWZhibo Wang

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Overview

Randomised trial enhanced antioxidant capacity and hydroxylysine levels in sows, indicating dietary synergy may boost female fertility.

Key Points

  • This research aims to explore how a high-fiber diet supplemented with N-carbamylglutamate affects reproductive efficiency in sows.
  • Sows were assigned to low-fiber or high-fiber groups with or without N-carbamylglutamate during gestation.
  • Serum sex hormones and antioxidants were measured.
  • Multi-omics approaches assessed the effects on uterine microbiota, metabolites, and gene expression.
  • High-fiber diet with N-carbamylglutamate increased total antioxidant capacity in serum.
  • Clostridium disporicum abundance elevated in the uterine microbiota.
  • Hydroxylysine identified as a key metabolite correlated with increased Clostridium disporicum.

Cite This Study

Liang et al. (2026) studied this question.

synapsesocial.com/papers/69fbe357164b5133a91a2a87https://doi.org/10.3390/antiox15050542
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