Analysis reveals delayed antibiotic administration increases hospital mortality in febrile neutropenia, suggesting urgency in treatment.
= 0.038). These findings were not confirmed in subgroups of patients with sepsis or bacteremia. Our study confirmed that TTA >4 h was associated with increased mortality but does not support recommendations of TTA ≤1 h in febrile neutropenia.
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Louw et al. (2026) studied this question.
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