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May 7, 2026IEEE Transactions on Neural Systems and Rehabilitation EngineeringOpen Access

Directional Tolerance of Electrode Displacement in STN-DBS: An Analysis Based on Volume of Tissue Activated

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Authors

CMChenghuai MoWHW W HuYXYuhai Xie

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Overview

This analysis demonstrates directional electrode displacements affect activation volume in Parkinson's, indicating the need for precise placement.

Key Points

  • This research aims to evaluate how directional electrode displacements in the STN impact stimulation efficacy and volume.
  • Evaluated electrode displacements within the subthalamic nucleus (STN)
  • Modeled stimulation fields using the Lead-DBS toolbox
  • Quantified volume of tissue activated (VTA) in STN functional subregions
  • Directional displacements impacted VTA patterns within the STN
  • Anterolateral displacement reduced VTA in the motor subregion
  • Medial and anterior displacements increased VTA in associative and limbic subregions

Cite This Study

Mo et al. (2026) studied this question.

synapsesocial.com/papers/69fbe3ca164b5133a91a31b9https://doi.org/10.1109/tnsre.2026.3689561
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