Investigation of VIM-1-producing Enterobacter spp. across Switzerland: clonal dissemination and plasmid transmission

Helena M. B. Seth-Smith; Mariella Greutmann; Jacqueline Findlay; Christiane Beckmann; Livia Berlinger; Silvio D. Brugger; Riccarda Capaul; Gilbert Greub; Eva Grüner; Peter M. Keller; Oliver Nolte; Tim Roloff; Sarah Tschudin-Sutter; Walter Zingg; Patrice Nordmann; Laurent Poirel; Adrian Egli; on behalf of the NARA Network

doi:10.1128/aac.01827-25

Key Points

To investigate the spread of VIM-1-producing Enterobacter species across Switzerland and their plasmid transmission.
Conducted genomic surveillance of Enterobacter spp. in Switzerland
Analyzed clonal dissemination patterns of VIM-1 producers
Evaluated the role of IncHI2 plasmids in transmission
Identified widespread clonal dissemination of VIM-1-producing Enterobacter
Highlighted the significance of IncHI2 plasmids in the outbreak
Emphasized the need for enhanced genomic surveillance for better outbreak response

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Implication

Investigation reveals clonal dissemination of VIM-1 in Enterobacter, suggesting enhanced genomic surveillance is needed.

Abstract

Enterobacterales in Switzerland, mediated by IncHI2 plasmids. These findings highlight the need for plasmid-focused genomic surveillance to complement clonal typing in CPE outbreak investigations.

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Cite This Study

Seth-Smith et al. (2026) studied this question.

synapsesocial.com/papers/69fbefa3164b5133a91a39d4 https://doi.org/10.1128/aac.01827-25

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Investigation of VIM-1-producing Enterobacter spp. across Switzerland: clonal dissemination and plasmid transmission

Key Points

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Implication

Abstract

Discussion

Cite This Study

Investigation of VIM-1-producing Enterobacter spp. across Switzerland: clonal dissemination and plasmid transmission

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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