To investigate the spread of VIM-1-producing Enterobacter species across Switzerland and their plasmid transmission.
Conducted genomic surveillance of Enterobacter spp. in Switzerland
Analyzed clonal dissemination patterns of VIM-1 producers
Evaluated the role of IncHI2 plasmids in transmission
Identified widespread clonal dissemination of VIM-1-producing Enterobacter
Highlighted the significance of IncHI2 plasmids in the outbreak
Emphasized the need for enhanced genomic surveillance for better outbreak response
Abstract
Enterobacterales in Switzerland, mediated by IncHI2 plasmids. These findings highlight the need for plasmid-focused genomic surveillance to complement clonal typing in CPE outbreak investigations.