This commentary evaluates the implications of spatial dynamics in deep brain stimulation on Parkinson's treatment.
Analysis of the commentary on basal ganglia activity and its relationship to motor states in Parkinson's disease.
Discussion on the closed-loop stimulation approach and its relevance to spatial propagation.
Spatial propagation of movement-related activity is linked to parkinsonian motor states.
Closed-loop deep brain stimulation could enhance therapeutic outcomes by targeting these dynamics.
Abstract
This scientific commentary refers to ‘Spatial propagation of movement-related basal ganglia activity predicts parkinsonian motor state’ by Averna et al. (https://doi.org/10.1093/brain/awag019).