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May 7, 2026Green Chemistry0 citations

Structure-Guided Engineering of an Aromatic Dioxygenase from Coniochaeta pulveracea for Improved Catalysis of Lignin-Related Aromatic Olefins

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LYLei YuYMYunjian MaCFChenhao Feng

Key Points

  • To enhance the catalytic properties of an aromatic dioxygenase from Coniochaeta pulveracea for better processing of lignin-related compounds.
  • Structure-guided engineering of aromatic dioxygenase
  • Characterization of catalytic activity
  • Assessment of coenzyme-independent properties
  • Increased catalytic efficiency observed in engineered dioxygenase
  • Enhanced oxidative cleavage of C=C bonds in aromatic olefins
  • Production of valuable aldehydes and ketones improved

Abstract

Aromatic dioxygenases (ADOs) catalyse the oxidative cleavage of C=C bonds in aromatic olefins, producing valuable aldehydes or ketones. Due to their coenzyme independence, ADOs are attractive catalysts. However, the limited...

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Cite This Study

Yu et al. (2026) studied this question.

synapsesocial.com/papers/69fbefef164b5133a91a4022https://doi.org/10.1039/d6gc00126b
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