No obesity paradox in out-of-hospital cardiac arrest: Data from the Swedish registry of cardiopulmonary resuscitation
Why the study?
It is unclear whether the obesity paradox exists in out-of-hospital cardiac arrest and whether concomitant diabetes confers additional risk.
Does obesity, with or without diabetes, reduce 30-day survival in patients with out-of-hospital cardiac arrest?
Population
55,483 patients with OHCA in the Swedish Registry of Cardiopulmonary Resuscitation
Comparison
Obesity only, T1D only, T2D only, or obesity with diabetes vs other
Design
Registry-based observational cohort study
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
Obesity may worsen 30-day survival after out-of-hospital cardiac arrest; challenges obesity paradox but remains hypothesis-generating.
Structured PICO
Does obesity, with or without diabetes, reduce 30-day survival in patients with out-of-hospital cardiac arrest?
P
Population
55,483 patients with out-of-hospital cardiac arrest (OHCA) reported to the Swedish Registry of Cardiopulmonary Resuscitation between 2010 and 2020.
I
Intervention
Obesity with or without diabetes (groups: obesity only, type 1 diabetes only, type 2 diabetes only, obesity and any diabetes)
C
Comparator
Other (patients without obesity or diabetes)
O
Outcome
30-day survivalhard clinical
In patients with out-of-hospital cardiac arrest, obesity is associated with a 30% reduction in 30-day survival, refuting the existence of an obesity paradox in this population.
Cite This Study
Hjalmarsson et al. (2023) studied this question.