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May 7, 2026Emerging Microbes & Infections0 citationsOpen Access

A copper uptake ABC transport system is essential for Mycobacterium tuberculosis virulence

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ZXZhihong XuShanghai Jiao Tong UniversityHTHuang TangShanghai Jiao Tong UniversityMYMeiyi YanChinese Academy of Medical Sciences & Peking Union Medical College

Key Points

  • This research aims to understand the role of the copper uptake ABC transport system in the virulence of Mycobacterium tuberculosis.
  • Investigated the function of copper uptake ABC transport system in Mycobacterium tuberculosis.
  • Utilized genetic and biochemical analyses to assess virulence mechanisms.
  • Demonstrated that disruption of the copper uptake system significantly reduced virulence in Mycobacterium tuberculosis.

Abstract

virulence. Taken together, these findings demonstrate that mycobacteria utilize the copper uptake ABC transport system to facilitate pathogenesis.

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Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/69fc2c1f8b49bacb8b347bffhttps://doi.org/10.1080/22221751.2026.2668753
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