Clinical features and risk factors of adenovirus-related plastic bronchitis in children

BACKGROUND: To analyze the clinical characteristics of children with adenoviral pneumonia, identify independent risk factors for early prediction of plastic bronchiolitis (PB), and develop a predictive nomogram. METHODS: This retrospective study analyzed the clinical data of children diagnosed with adenoviral pneumonia. Patients were categorized into PB and non-PB groups. General characteristics, clinical symptoms, laboratory findings, and imaging results were compared between the two groups. Multivariate logistic regression was used to identify significant risk factors, and a nomogram model was constructed. RESULTS: = 7.207). CONCLUSIONS: Diminished breath sounds, D-D levels, and LDH levels are independent risk factors for PB in children with adenoviral pneumonia. The developed nomogram demonstrates high predictive accuracy and good calibration, providing a valuable tool for early prediction and clinical decision-making. Future studies should validate this nomogram in larger and diverse populations.