Why the study?
Information was sparse regarding the safety of early primary discharge from the emergency department after ruling out myocardial infarction in suspected acute coronary syndrome across routine clinical settings.
Does a dual marker strategy using copeptin and troponin for early discharge safely reduce emergency department stay compared to conventional workup in patients with suspected ACS?
Population
2294 patients with suspected ACS across 18 European emergency departments
Comparison
Primary dual marker strategy discharge vs conventional workup after dual marker measurement
Design
Prospective, multicentre European registry
Follow-up
30 days
Authors
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May support safe early discharge in suspected ACS; leaves open confirmation by randomized trials before practice change.
Does a dual marker strategy using copeptin and troponin for early discharge safely reduce emergency department stay compared to conventional workup in patients with suspected ACS?
The addition of copeptin to cardiac troponin testing supports safe early discharge and reduces emergency department length of stay in patients with suspected ACS under routine clinical conditions.
Giannitsis et al. (2019) studied this question.
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