Why the study?
Does pulmonary hypertension increase the risk of perioperative mortality in patients undergoing major joint replacement?
Population
1,030,635 entries for primary total hip arthroplasty and total knee arthroplasty from the US National…
Comparison
Presence of chronic pulmonary hypertension (PHTN) vs Matched patients without pulmonary hypertension…
Design
Cohort
Follow-up
in-hospital
Authors
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Supports enhanced preoperative risk stratification for PHTN patients undergoing THA/TKA; leaves open whether targeted interventions reduce mortality.
Does pulmonary hypertension increase the risk of perioperative mortality in patients undergoing major joint replacement?
Pulmonary hypertension is associated with a 4- to 4.5-fold increased risk of in-hospital mortality following major joint replacement surgery.
Memtsoudis et al. (2010) studied this question.
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