Why the study?
Is the deletion polymorphism of the ACE gene associated with an increased risk of left ventricular hypertrophy in middle-aged adults?
Is the deletion polymorphism of the ACE gene associated with an increased risk of left ventricular hypertrophy in middle-aged adults?
The DD genotype of the ACE gene is a potential genetic marker associated with an elevated risk of left ventricular hypertrophy, particularly in middle-aged men and those with normal blood pressure.
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Should not alter LVH risk assessment; leaves open whether ACE DD adds predictive value beyond traditional factors.
Schunkert et al. (1994) studied this question.
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