March 21, 2005European Heart JournalOpen Access

Relation of N-terminal pro B-type natriuretic peptide to progression of aortic valve disease

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Why the study?

Does NT-proBNP level reflect disease progression and response to valve replacement in patients with aortic valve disease?

Population

168 patients with aortic valve disease, including aortic stenosis, aortic regurgitation, and previous valve…

Comparison

Valve replacement (n=86) vs Conservative treatment (n=82)

Design

Cohort

Authors

MWMichael WeberSUNY Downstate Health Sciences University RARomán ArnoldCentro de Investigación en Red en Enfermedades Cardiovasculares MRMatthias RauUniversitätsklinikum Aachen

Discussion

Member takes

Implication

NT-proBNP may aid monitoring in aortic valve disease; leaves open prospective validation before guiding decisions.

Structured PICO

Does NT-proBNP level reflect disease progression and response to valve replacement in patients with aortic valve disease?

Population

168 patients with aortic valve disease, including aortic stenosis (n=109), aortic regurgitation (n=37), and previous valve replacement (n=22).

Intervention

Valve replacement (n=86)

Comparator

Conservative treatment (n=82)

Outcome

Relation of NT-proBNP values to the progression of aortic valve diseasesurrogate

NT-proBNP levels correlate with aortic valve disease severity, decreasing after valve replacement and increasing with conservative management, suggesting its utility for disease monitoring.

Cite This Study

Weber et al. (2005) studied this question.

synapsesocial.com/papers/69fd564d5c6eda2188019136 https://doi.org/10.1093/eurheartj/ehi236

Topics

Echocardiography

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March 21, 2005European Heart JournalOpen Access

Relation of N-terminal pro B-type natriuretic peptide to progression of aortic valve disease

View Full Paper

Ask AI

Bookmark

Why the study?

Does NT-proBNP level reflect disease progression and response to valve replacement in patients with aortic valve disease?

Population

168 patients with aortic valve disease, including aortic stenosis, aortic regurgitation, and previous valve…

Comparison

Valve replacement (n=86) vs Conservative treatment (n=82)

Design

Cohort

Authors

MWMichael WeberSUNY Downstate Health Sciences University RARomán ArnoldCentro de Investigación en Red en Enfermedades Cardiovasculares MRMatthias RauUniversitätsklinikum Aachen

Discussion

Member takes

Implication

NT-proBNP may aid monitoring in aortic valve disease; leaves open prospective validation before guiding decisions.

Structured PICO

Does NT-proBNP level reflect disease progression and response to valve replacement in patients with aortic valve disease?

Population

168 patients with aortic valve disease, including aortic stenosis (n=109), aortic regurgitation (n=37), and previous valve replacement (n=22).

Intervention

Valve replacement (n=86)

Comparator

Conservative treatment (n=82)

Outcome

Relation of NT-proBNP values to the progression of aortic valve diseasesurrogate

NT-proBNP levels correlate with aortic valve disease severity, decreasing after valve replacement and increasing with conservative management, suggesting its utility for disease monitoring.

Cite This Study

Weber et al. (2005) studied this question.

synapsesocial.com/papers/69fd564d5c6eda2188019136 https://doi.org/10.1093/eurheartj/ehi236

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Echocardiography

View Full Paper

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