Fluorescence Dynamics Imaging Reveals Inflammation Driven by Ferroptosis through a MAO/ONOO – Dual-Responsive Probe

Key Points

• The aim is to explore how ferroptosis contributes to inflammation and assess potential interventions.
• Utilized a dual-responsive probe for fluorescence dynamics imaging.
• Investigated the role of MAO and ONOO in the inflammatory pathway.
• Assessed the effects of inhibiting ferroptosis on inflammation.
• Inhibition of ferroptosis significantly reduced inflammation levels.
• Demonstrated a clear link between MAO activity and inflammation exacerbation.
• Established fluorescence imaging as a viable tool for studying acute inflammation mechanisms.