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Uncovers ERα's role in antigen processing in dendritic cells, suggesting a new strategy for immune therapy.
T cells. Our work thus uncovers a non-canonical role of ERα in phagosome integrity as a checkpoint for antigen cross-presentation in DCs, and implicates ERα-targeted DC vaccines as a potential immunotherapeutic strategy.
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Liu et al. (2026) studied this question.
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