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May 5, 2026Journal of the American Chemical Society

Fluorinated Biradicals for ¹⁹ F Magic-Angle Spinning Dynamic Nuclear Polarization-Enhanced NMR Spectroscopy

Judith Schlagnitweit Annabelle Peyronnet Gilles Casano David Gajan M. Balodis Amrit Venkatesh Guido Pintacuda Olivier Ouari Anne Lesage

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Key Points

The aim is to explore fluorinated biradicals in enhancing NMR spectroscopy via dynamic nuclear polarization.
Used fluorinated biradicals to enhance DNP in nuclear magnetic resonance.
Focused on pharmaceutical analysis where probe limitations exist.
Investigated indirect polarization transfer challenges related to protons.
Demonstrated improved signal detection in NMR due to enhanced polarization.
Facilitated analysis in settings where traditional methods are limited.

Implication

Demonstrates DNP enhancement in NMR spectroscopy for pharmaceuticals, indicating improved analysis techniques.

Abstract

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Cite This Study

Schlagnitweit et al. (2026) studied this question.

synapsesocial.com/papers/69fd7e00bfa21ec5bbf06414 https://doi.org/10.1021/jacs.6c04081

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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