Exploratory observational study assesses hypertonic dextrose's effect in adhesive small bowel obstruction, suggesting new treatment avenues.
Adhesive small bowel obstruction (ASBO) is commonly managed conservatively, with adjuncts such as CT scan with per-oral water-soluble contrast, which are diagnostic and in some cases therapeutic. However, these may not be consistently available in low-resource settings. Hypertonic solutions have been shown to influence intestinal oedema and function, but the role of intravenous hypertonic dextrose is unclear. We describe an observational experience of adjunctive 25% dextrose (40 mL daily for 3 days) in selected patients with ASBO managed non-operatively at a tertiary centre in central India.
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Sharma et al. (2026) studied this question.
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