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Systematic review demonstrates the need for standardized evaluation workflows for DL-based MRI synthesis, indicating barriers to clinical use.
Limited rates of reader studies and external validation represent key barriers to clinical translation of DL-based postcontrast MRI synthesis. Standardized evaluation workflows incorporating whole-image metrics, pathology-specific assessment, and reader studies are essential before these techniques can be translated into clinical practice.
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Dogra et al. (2026) studied this question.
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