Hemodynamic Determinants of Coronary Flow: Effect of Changes in Aortic Pressure and Cardiac Output on the Relationship Between Myocardial Oxygen Consumption and Coronary Flow

Although the general dependence of coronary flow on myocardial qo 2 was confirmed in an in situ heart preparation, changes in aortic pressure and cardiac output were observed to be capable of influencing this relationship. Neither myocardial qo 2 nor coronary flow were found to be dependent on left ventricular filling pressure.