Implementation of a protocol using ketamine-propofol (‘ketofol’) in a 1 to 4 ratio for procedural sedation in adults at a university hospital emergency department – report on safety and effectiveness

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: A feasibility trial of an implemented protocol for ketofol procedural sedation in adults showed only minor respiratory events, a low incidence of agitation or hallucinations, minimal recall and a high success and physician satisfaction rate. Despite a non-consecutive and limited sample used, ketofol in a 1 to 4 ratio appears safe and effective for use in the emergency department.