Psychosocial Outcomes of Velopharyngeal Insufficiency Treatment in Patients with Cleft Palate: A Systematic Review

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Key Points

To synthesize pediatric cleft-related VPI quality-of-life outcomes using VELO and PedsQL instruments.
Comprehensive literature search on PubMed, EMBASE, Google Scholar, Cochrane Library, and ProQuest.
Included studies evaluated psychosocial outcomes using VELO or PedsQL scores in VPI patients.
Assessed risk of bias via the Newcastle-Ottawa Scale.
Thirteen studies included with 617 patients providing 1,126 reports on VELO and PedsQL.
Preoperative VELO scores were 71.7 for child self-report and 67.3 for parent proxy, with a postoperative mean of 73.4 (parent-only).
Pooled change in VELO was +46.3, while PedsQL preoperative mean was 64.4, showing a postoperative change of +10.1 from one study.

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Systematic review examines psychosocial outcomes, highlighting preoperative burden and postoperative improvements in cleft palate patients.

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Lee et al. (2026) studied this question.

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