The overall five-year prevalence of acute coronary syndrome in Colombia was 7.1 cases per 1,000 individuals, with atrial fibrillation showing the strongest comorbidity association (PR 13.5).
Cross-Sectional (n=34,985,391)
This nationwide Colombian study highlights a 5-year ACS prevalence of 7.1 per 1,000 adults, with atrial fibrillation, peripheral artery disease, and hypertension being the most strongly associated comorbidities.
Introduction: Acute coronary syndrome (ACS) is a leading cause of morbidity and mortality worldwide; however, data on ACS in Colombia is limited and outdated.Objective: To determine the prevalence of acute coronary syndrome (ACS) in Colombia, using a nationally representative database, as well as its association with its main comorbidities: hypertension, dyslipidemia, obesity, diabetes, sleep apnea, peripheral artery disease (PAD), and atrial fibrillation (AF), by age group and sex.Methods: This descriptive, cross-sectional study used data from the Ministry of Health for 2019-2023, including all individuals aged 20-100 who had had any contact with the healthcare system.The five-year prevalence of ACS and each of the conditions of interest was estimated and analyzed by sex and 10-year age groups.Subsequently, the prevalence ratio (PR) for ACS was calculated for each comorbidity.Results: During the five-year period, 247,818 individuals (58% males), from a total population of 34,985,391, were diagnosed with ACS; the mean age was 64.2 in males and 66.5 in females.The overall five-year prevalence was 7.1 cases per 1,000 individuals over the age of 20 (males: 8.9; females: 5.6).Hypertension, diabetes, dyslipidemia, and obesity were more prevalent in females.Atrial fibrillation had the highest PR (13.5), followed by PAD (10.1), hypertension (9.8), diabetes (4.8), sleep apnea (3.2), obesity (1.5), and dyslipidemia (1.5).Prevalence ratios were higher in younger people and in males.Conclusions: This large nationwide database shows the magnitude of the association of ACS with a set of chronic conditions.
Silva‐Buriticá et al. (2026) conducted a cross-sectional in Acute coronary syndrome (n=34,985,391). Comorbidities (e.g., atrial fibrillation, peripheral artery disease, hypertension) vs. Individuals without the respective comorbidities was evaluated on Five-year prevalence of acute coronary syndrome (cases per 1,000 individuals). The overall five-year prevalence of acute coronary syndrome in Colombia was 7.1 cases per 1,000 individuals, with atrial fibrillation showing the strongest comorbidity association (PR 13.5).