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May 9, 2026Open Access

Quality assessment of devices for in vitro diagnosis of Chagas disease

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Authors

AOAna ObraczkaAPAline PaulaBSBrenda Sousa

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Overview

Randomized trial evaluates in vitro diagnostic tests for Chagas disease, indicating high quality standards for diagnosis.

Key Points

  • This research aims to evaluate the quality of in vitro diagnostic tests for Chagas disease as part of the registration process with Anvisa.
  • A survey analyzed clinical sensitivity and specificity of tests at the National Institute for Health Quality Control from January 2023 to December 2025.
  • Tests that met sensitivity of 100% and specificity of at least 99% were deemed satisfactory.
  • 20 batches of various diagnostic tests were assessed, including rapid tests and chemical assays.
  • 19 out of 20 batches (95%) met the recommended sensitivity and specificity thresholds.
  • Only 1 batch (5%) received an unsatisfactory rating for efficacy.
  • All tests received were for pre-marketing analysis.

Cite This Study

Obraczka et al. (2026) studied this question.

synapsesocial.com/papers/69fecf49b9154b0b82876421https://doi.org/10.35259/isi.2026_76236
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